Basic Information
VIS ID
TVIS30008498
Fusion event
HIV-KLHL24 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
183395252/183677464 (Hg38)
End
183395252/183677464 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
KLHL24
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-183-5p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-190a-5p ; hsa-mir-190b ; hsa-mir-3611 ; hsa-mir-4428 ; hsa-mir-6888-5p ; hsa-mir-4670-3p ; hsa-mir-4501 ; hsa-mir-1305 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-548g-3p ; hsa-mir-3674 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-7157-5p ; hsa-mir-4310
Nearest miRNA
hsa-let-7g/Upstream/7162313; hsa-mir-1224/Downstream/209336;
Nearest TSS
ENST00000440867/Upstream/13363; ENST00000432781/Downstream/20354;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/40436, chr3-CpG: 63/Downstream/20350
Upstream sequence
AGAGTTTGTTCCATAATTGGTGCAATTCATGGGGGTGTGGTATTCTGAATTAAAGTGTCTTTCACTATATGATAATAGGCTAAGTCATTCTGGGTGTCTA
Downstream sequence
TAAATTCTAATATAGGCATTTTTAAGTACTCACAAATTCTTTCAGACCTAAAGATAGTATCCTTCTATTATATAAAGCCACCAAGATTTAATTTCTTCTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate