Basic Information
VIS ID
TVIS30008549
Fusion event
HIV-FBXL5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
15613066/15611443 (Hg38)
End
15613066/15611443 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
FBXL5
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-186-5p ; hsa-mir-93-5p ; hsa-mir-331-3p ; hsa-mir-218-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-31-3p ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-596 ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-3934-3p ; hsa-mir-767-3p ; hsa-mir-6787-3p ; hsa-mir-5690 ; hsa-mir-203a-3p ; hsa-mir-5680 ; hsa-mir-4801 ; hsa-mir-4731-3p
Nearest miRNA
hsa-mir-12113/Upstream/1983486; hsa-mir-12115/Downstream/4916832;
Nearest TSS
ENST00000502981/Upstream/15571; ENST00000507992/Downstream/33206;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/606306, chr4-CpG: 145/Downstream/43298
Upstream sequence
TTGTTCTGCCTGAGAAAAATTTTGTTGATTTTCCTGTCATCTTAAGGTGAACTGGGCACTCAAAGACAATAGGGCGCAGTATAAAAAGACAGGTACATAG
Downstream sequence
TAGTCTGAGCCATCTAAAATTTTCTCCAGTTATAAATACAGGAGGTTGATTTGCTTACTAATAACAGAAGAGCAGCTTTTTATGCTTCTGGGAAATTCAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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