Basic Information
VIS ID
TVIS30008567
Fusion event
HIV-KLHL5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
39073546/39071926 (Hg38)
End
39073546/39071926 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLHL5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-744-3p ; hsa-mir-4446-5p ; hsa-mir-4482-3p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-1298-5p ; hsa-mir-889-3p ; hsa-mir-205-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-5583-3p ; hsa-mir-4517
Nearest miRNA
hsa-mir-12113/Upstream/203799; hsa-mir-1243/Downstream/339984;
Nearest TSS
ENST00000502981/Upstream/8986; ENST00000515612/Downstream/31389;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/26478, chr4-CpG: 28/Downstream/98696
Upstream sequence
AGACTAGAAATATTCAGCAATGTATTCATTACAGTGAAAGTCTAATATAAAAGATTTGAATGATCTTATGTAATTTTCTGAAATATGATTTAGTGGTATC
Downstream sequence
ATATAAGCAAAACTAAGCAGAGATGTTAGATGTATTTCCTCTGTTGTTATGTAAAAGATCAAGTAGAAATCAGAGAGAAATATATTTTAAATGCTTCAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate