Basic Information
VIS ID
TVIS30008599
Fusion event
HIV-BMP2K integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
79768853/78847699 (Hg38)
End
79768853/78847699 (Hg38)
Orient
+
Location type
Intronic
Target gene
BMP2K
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-let-7e-5p ; hsa-mir-1228-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-6885-3p ; hsa-mir-6771-3p ; hsa-mir-1909-5p ; hsa-mir-4693-3p ; hsa-mir-551b-5p ; hsa-mir-4311 ; hsa-mir-548c-3p ; hsa-mir-4477a ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-606 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-4672 ; hsa-mir-466 ; hsa-mir-3941 ; hsa-mir-610 ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-5697 ; hsa-mir-101-5p ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-1245a
Nearest miRNA
hsa-mir-12113/Upstream/2272073; hsa-mir-1243/Downstream/3905638;
Nearest TSS
ENST00000502981/Upstream/71321; ENST00000515075/Downstream/3193;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/70895, chr4-CpG: 68/Downstream/91360
Upstream sequence
CATAACTCTTAAGTAATTACACAATAATTTTCTGGAGTATTTTAGGGTCTTTTTAATGGAAATTGATATGAGTAAATGTTTTTCTAATTACAGTATAAAC
Downstream sequence
ATACCATTGACTAGCTTTTGTATATTGAGGGTCTTTATCATTTAGCCTGTATATATCTGGATATAATTACTGAGATAGACCATATTTCTTTATAGTTGAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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