Basic Information
VIS ID
TVIS30008671
Fusion event
HIV-LRBA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
151771638/150850486 (Hg38)
End
151771638/150850486 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRBA
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-93-3p ; hsa-mir-769-5p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-12113/Upstream/3067818; hsa-mir-1305/Downstream/1638841;
Nearest TSS
ENST00000502981/Upstream/949; ENST00000503002/Downstream/164781;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/266553, chr4-CpG: 89/Downstream/165015
Upstream sequence
cccggccTATACCAATTATTTTTTAATACTTCTAGTAATAAACCAACTTGATAAACCTACCTTCTGGTGAATTCCGTGCCATAAAATTGCTACAGGAAAT
Downstream sequence
CTACTACAAATTTTTTTAAAAGAGAAACCTCTGCTTTTCACATTTTTGTAATCCAGATAAGGATTCCATTCTTATAATGGAGAATAAAAGTGAATTCAGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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