Basic Information
VIS ID
TVIS30008679
Fusion event
HIV-PLRG1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
155461999/154540847 (Hg38)
End
155461999/154540847 (Hg38)
Orient
+
Location type
Exonic
Target gene
PLRG1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-5701 ; hsa-mir-3908 ; hsa-mir-580-5p ; hsa-mir-4517 ; hsa-mir-195-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-563 ; hsa-mir-380-5p ; hsa-mir-4495 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-3140-3p ; hsa-mir-5580-3p ; hsa-mir-4789-3p ; hsa-mir-4482-3p ; hsa-mir-7159-3p
Nearest miRNA
hsa-mir-12113/Upstream/2004331; hsa-mir-1305/Downstream/4587955;
Nearest TSS
ENST00000502981/Upstream/575; ENST00000498375/Downstream/89;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/48606, chr4-CpG: 40/Downstream/9134
Upstream sequence
AGTTCACAATGTTTTAAATCCTTAACTCCAAACTTACCTTATTGTATTCGAGATCCCAGCATTTCACTTGTTTGTCTTCTCCACAAGAGAACAGATATGG
Downstream sequence
GCTCCTTGTGCTTACTATCACGCCCCGCACAGTACTAATATGCCCAGTCAATGACAGTTTTAATTTGCCACTAGCCAAGTCCCAGATCTGCAATCAAAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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