Basic Information
VIS ID
TVIS30008755
Fusion event
HIV-PARP8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
49972780/50676946 (Hg38)
End
49972780/50676946 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
PARP8
miRNAs that regulate target gene
hsa-mir-145-5p
Nearest miRNA
hsa-mir-10397/Upstream/12119385; hsa-mir-103a-1/Downstream/3274558;
Nearest TSS
ENST00000502646/Upstream/9053; ENST00000508923/Downstream/183074;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9003, chr5-CpG: 53/Downstream/292305
Upstream sequence
CCTTTTTTAAGGCAATGTCAGTTATTAAGCTTTAGGGAACCACATGCCACTTTAGGTAACAGATGATTGGAGAGATTGAAGAGTGAAGTCCCTGCTTTAA
Downstream sequence
AGTGTACTCCTGTGGACACAGTAATACATATACTTAAAATGGTTCATGTTAAGAGTAGGTATATTTCTATCTAAATACTCTGTAGCTTTTGTGATTCAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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