Basic Information
VIS ID
TVIS30008765
Fusion event
HIV-MTREX integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
54605264/55309436 (Hg38)
End
54605264/55309436 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
MTREX
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10397/Upstream/137083; hsa-mir-103a-1/Downstream/199414;
Nearest TSS
ENST00000502646/Upstream/1367; ENST00000502953/Downstream/12891;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1360, chr5-CpG: 23/Downstream/221346
Upstream sequence
TTTAGGAAAATTAATTTGGCAGTGGTTGGCAGAGTACTATAATAGTATAGGGAAAGAAGATAGACAGTGAGAAAGTAAATTAGGAAATTATGTTAGTTAT
Downstream sequence
CTGGTTGTAAAGATGAAAAGAACCTCAACTCAGGCAGTGGCAGAGGAATGGAAAGGTACGAACATGTTAAGGAAAAAATGGACAGGCCTTCATTAATTAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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