Basic Information
VIS ID
TVIS30008791
Fusion event
HIV-POLK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74871681/75575856 (Hg38)
End
74871681/75575856 (Hg38)
Orient
-
Location type
Intronic
Target gene
POLK
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-132-3p
Nearest miRNA
hsa-mir-10397/Upstream/2697193; hsa-mir-103a-1/Downstream/7264299;
Nearest TSS
ENST00000502646/Upstream/23385; ENST00000502567/Downstream/21258;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/63707, chr5-CpG: 39/Downstream/35605
Upstream sequence
ACCATTTTCTAAAATTCCCTTTGACTCAGCTGTTCATAATTATATTAAGCTAAAAACCTTTGTTTTTATAAAAGAAGAAACAGTTTTCTCATGATACAGT
Downstream sequence
AGACAGTTTTAAAAGCTAAATGGAAGCTTAACGTAATTCAGCAAATATGTTTTCTAATATAAAttttttttgaggcagggtctcactctgtcacccaagc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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