Basic Information
VIS ID
TVIS30008794
Fusion event
HIV-TBCA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
77020552/77724727 (Hg38)
End
77020552/77724727 (Hg38)
Orient
-
Location type
Intronic
Target gene
TBCA
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-501-5p ; hsa-mir-186-5p ; hsa-mir-335-3p ; hsa-mir-6875-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-103a-2-5p ; hsa-mir-4778-3p ; hsa-mir-6787-3p ; hsa-mir-3691-3p ; hsa-mir-1250-3p ; hsa-mir-1264 ; hsa-mir-510-3p ; hsa-mir-494-3p ; hsa-mir-186-3p ; hsa-mir-4733-5p ; hsa-mir-3156-5p
Nearest miRNA
hsa-mir-10397/Upstream/4846064; hsa-mir-103a-1/Downstream/5115428;
Nearest TSS
ENST00000502646/Upstream/9410; ENST00000510030/Downstream/51534;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/78664, chr5-CpG: 86/Downstream/51094
Upstream sequence
AGTCATACCAGTTCCCTTAACTCCCTTACCACATGAAATGGCAAAAGCTACTAGAAGTTTATTATAGTATATTATTTCAGTAAATCCTGGATATTCAGAC
Downstream sequence
ACACTTTATAAAAATTAAAACTAAAATGGCACTTCCTGTAACAACATTACTGTTTGCCTTTTGCCCTGATACACTTCAGGAAACGTGTACACTAGAGTGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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