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TVIS30008874
Basic Information
VIS ID
TVIS30008874
Fusion event
HIV-AFF4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
132274408/132938716 (Hg38)
End
132274408/132938716 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
AFF4
miRNAs that regulate target gene
hsa-mir-374b-5p
;
hsa-mir-421
;
hsa-mir-335-5p
;
hsa-mir-128-3p
;
hsa-mir-101-3p
;
hsa-mir-27a-3p
;
hsa-mir-532-3p
;
hsa-mir-18a-5p
;
hsa-let-7b-5p
;
hsa-mir-3156-5p
;
hsa-mir-7161-3p
;
hsa-mir-126-5p
;
hsa-mir-466
;
hsa-mir-4789-3p
;
hsa-mir-101-5p
;
hsa-mir-548c-3p
;
hsa-mir-519d-5p
;
hsa-mir-4795-3p
;
hsa-mir-5695
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-3606-3p
;
hsa-mir-425-5p
;
hsa-mir-4659a-5p
;
hsa-mir-4659b-5p
;
hsa-mir-205-5p
;
hsa-mir-142-3p
;
hsa-mir-4424
;
hsa-mir-642b-3p
;
hsa-mir-642a-3p
;
hsa-mir-936
;
hsa-mir-4776-3p
;
hsa-mir-5590-5p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-4643
;
hsa-mir-302f
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-587
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-627-3p
;
hsa-mir-6832-3p
;
hsa-mir-3938
;
hsa-mir-30e-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30c-5p
;
hsa-mir-30a-5p
;
hsa-mir-27b-3p
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-16-5p
;
hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10397/Upstream/573117; hsa-mir-103a-1/Downstream/488880;
Nearest TSS
ENST00000502646/Upstream/976;
ENST00000607688/Downstream/24797;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/71655
,
chr5-CpG: 76/Downstream/24551
Upstream sequence
AAACCTCCTGATTTGCATACTAAGTGTCATGCAATAAAAGCAATTTAACGGCCTGAgcggctcacgcctgtaaacccagcactttgggaggccgaggtgg
Downstream sequence
gcagatcacaaggtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaatacaaaaaattagccaggtgcagtggcaggcg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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