Basic Information
VIS ID
TVIS30008888
Fusion event
HIV-MATR3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
138633299/139297610 (Hg38)
End
138633299/139297610 (Hg38)
Orient
+
Location type
Intronic
Target gene
MATR3
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-24-3p ; hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-125b-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-mir-16-1-3p ; hsa-mir-302c-5p ; hsa-mir-3143 ; hsa-mir-4659a-3p ; hsa-mir-4659b-3p ; hsa-mir-6875-3p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-2276-3p ; hsa-mir-4708-3p ; hsa-mir-4772-3p ; hsa-mir-4330 ; hsa-mir-10b-3p ; hsa-mir-1245b-3p ; hsa-mir-4802-3p ; hsa-mir-33a-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-338-5p ; hsa-mir-5094 ; hsa-mir-543
Nearest miRNA
hsa-mir-10397/Upstream/1649961; hsa-mir-103a-1/Downstream/1266061;
Nearest TSS
ENST00000502646/Upstream/2972; ENST00000514402/Downstream/9806;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2991, chr5-CpG: 87/Downstream/44034
Upstream sequence
TTATGTGTAATTTAAAAAATTGAGTATAAGTGTTAGGTTTTAACGCATTTCTATTATAATCCTATTTGTAATACAGTAAAAGTTACATGATAAAGTGCTG
Downstream sequence
TTATCTGACCTAACCTGAATATAATTTATTACTGTGGCACTTCTGTGTGGATGGAGTGCGGAGTGCCTTTGATGTGATGTATAATTTTCCAGTTGTACAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate