Basic Information
VIS ID
TVIS30008919
Fusion event
HIV-ITK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
156656731/157229721 (Hg38)
End
156656731/157229721 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITK
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-6083 ; hsa-mir-7111-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-5196-3p ; hsa-mir-3183 ; hsa-mir-3074-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p
Nearest miRNA
hsa-mir-10397/Upstream/2400181; hsa-mir-103a-1/Downstream/3244681;
Nearest TSS
ENST00000502646/Upstream/5341; ENST00000520173/Downstream/10372;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/86665, chr5-CpG: 91/Downstream/36081
Nearest cancer related gene
ITK(OG, No orient, 0)
Upstream sequence
agactaaagaggtcgggcgcagtggcccacacctgtagtctcaacactttgggaggctgaggcaggtggatcacctgagatcaggagtttgagaccaggc
Downstream sequence
tgaccaacatggtgaaaccaccgtctctactaaaaatacagaattatccgggtgtgatggcacacgcctgtagtcccagatacttgggaggctgaggcag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate