Basic Information
VIS ID
TVIS30008950
Fusion event
HIV-MAML1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
179162095/179735094 (Hg38)
End
179162095/179735094 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
MAML1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-197-3p ; hsa-mir-92a-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-4291 ; hsa-mir-130b-5p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-1179 ; hsa-mir-5003-3p
Nearest miRNA
hsa-mir-10397/Upstream/3105594; hsa-mir-1229/Downstream/63184;
Nearest TSS
ENST00000502646/Upstream/2244; ENST00000507385/Downstream/33758;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1561, chr5-CpG: 124/Downstream/60513
Upstream sequence
GAATAAAAAGAAATGAGTGTGGACATGAAAATACAGTATTTCgggggaagggatagcattgggagatatacctaatgctagatgacgagttagtgggtgc
Downstream sequence
agcgcaccagcatggcacatgtatacgtatgtaactaacctgcacattgtacacatgtaccctaaaacttaaagtatgataataataaataaaTAAATAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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