Basic Information
VIS ID
TVIS30009014
Fusion event
HIV-DDR1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30860356/30892579 (Hg38)
End
30860356/30892579 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
DDR1
miRNAs that regulate target gene
hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-335-5p ; hsa-let-7g-5p ; hsa-mir-1286 ; hsa-mir-1321 ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-3612 ; hsa-mir-3689d ; hsa-mir-4257 ; hsa-mir-4419a ; hsa-mir-4459 ; hsa-mir-4510 ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6799-5p ; hsa-mir-6847-5p ; hsa-mir-6851-5p ; hsa-mir-6873-5p ; hsa-mir-873-5p ; hsa-mir-3663-3p ; hsa-mir-3667-3p ; hsa-mir-4645-5p ; hsa-mir-4650-5p ; hsa-mir-4673 ; hsa-mir-6501-3p ; hsa-mir-6734-3p ; hsa-mir-6868-3p ; hsa-mir-6871-3p
Nearest miRNA
hsa-mir-3143/Upstream/1607; hsa-mir-10398/Downstream/462645;
Nearest TSS
ENST00000381078/Upstream/1152; ENST00000514534/Downstream/41;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/8162, chr6-CpG: 27/Downstream/15286
Upstream sequence
TGCAGTGCCGCTTCCTCTTTGCGGGGCCCTGGTTACTCTTCAGCGAAATCTCCTTCATCTCTGGTAAGCCCTGGAGTAGCCCAGTCTCCAGTCCCTGAAA
Downstream sequence
TTGACAACTGATTTCATTCCTAACCCTGCAGTGTCCCTAAAATACTCATTCCTTGCATTATATCTACCCATCACCCACCGAAACTTCTCAATTAGGGGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate