Basic Information
VIS ID
TVIS30009043
Fusion event
HIV-ZNF76 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
35232908/35265131 (Hg38)
End
35232908/35265131 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
ZNF76
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-93-5p ; hsa-mir-7159-3p ; hsa-mir-592 ; hsa-mir-7108-5p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-3157-5p ; hsa-mir-597-5p ; hsa-mir-663b ; hsa-mir-4691-3p ; hsa-mir-511-3p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-449b-3p
Nearest miRNA
hsa-mir-1236/Upstream/1024395; hsa-mir-10398/Downstream/205377;
Nearest TSS
ENST00000381078/Upstream/5357; ENST00000482946/Downstream/5281;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/5057, chr6-CpG: 44/Downstream/52994
Upstream sequence
ttcactgattcattcatCCCacaaatatttggtgaatatctgctgtgtgccaggtacttttctaggtactgggaatagagcagtgagctcactgtttgag
Downstream sequence
gaatggacagggtagagacagacaataaacaaataagtaaaatatatattgagaaaattaagcagagaagggagatagaaagtgccaggagtaggccagg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate