Basic Information
VIS ID
TVIS30009072
Fusion event
HIV-ZNF318 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
43317491/43349753 (Hg38)
End
43317491/43349753 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
ZNF318
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-197-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-5683 ; hsa-mir-382-5p ; hsa-mir-495-5p ; hsa-mir-2681-5p
Nearest miRNA
hsa-mir-10398/Upstream/1616143; hsa-mir-10524/Downstream/84789;
Nearest TSS
ENST00000381078/Upstream/6917; ENST00000502549/Downstream/19690;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/40832, chr6-CpG: 148/Downstream/18989
Upstream sequence
TCTCTGTTCTTTCATACTATCAGTATTTAGGAGCCTTGTTATGTTCTTTTCCTCACTGTGTATGTGAATTCCTAAAAGCATAAAGAAATGGAATAAAAAG
Downstream sequence
GAAGGCATCAGggaacatttttgtgtgtgtgtgccaaatttaaggaaagaccagacactgtggttcatgcctgtaatcccagtgctttgggaggctgaga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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