Basic Information
VIS ID
TVIS30009201
Fusion event
HIV-MTHFD1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
151397735/151076599 (Hg38)
End
151397735/151076599 (Hg38)
Orient
+
Location type
Intronic
Target gene
MTHFD1L
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-887-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-218-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-3622a-5p ; hsa-mir-29b-2-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-92a-1-5p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-6509-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-4760-3p
Nearest miRNA
hsa-mir-10398/Upstream/10392716; hsa-mir-1202/Downstream/26076;
Nearest TSS
ENST00000381078/Upstream/20542; ENST00000490177/Downstream/121039;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/209623, chr6-CpG: 25/Downstream/14268
Upstream sequence
aattaattgggcatggtggcacacgcctgtaatcccagctactcgggaggctgaggcccgagaattgcttgaacccaggaaacagaggttgcagtgagcc
Downstream sequence
aagattgtaccactgcactccagcctgggtgacagagtgatactctgtctaaaaaaaaaaaaaaaaaagactgaccataccaaatgttggcaaggatgtg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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