Basic Information
VIS ID
TVIS30009213
Fusion event
HIV-EZR integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
159231389/158810357 (Hg38)
End
159231389/158810357 (Hg38)
Orient
+
Location type
Intronic
Target gene
EZR
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-204-5p ; hsa-mir-18a-5p ; hsa-mir-1180-3p ; hsa-mir-615-3p ; hsa-mir-328-3p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-222-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-184 ; hsa-mir-205-5p ; hsa-mir-6818-5p ; hsa-mir-1257 ; hsa-mir-3622b-5p ; hsa-mir-4294 ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-6730-3p ; hsa-mir-4766-5p ; hsa-mir-3677-5p
Nearest miRNA
hsa-mir-10398/Upstream/45604; hsa-mir-1913/Downstream/7698997;
Nearest TSS
ENST00000381078/Upstream/20883; ENST00000451712/Downstream/7654;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/165595, chr6-CpG: 147/Downstream/7889
Upstream sequence
CTGTTTGCCTGTAAGTGTTAAGAACGGGTTAATGAATAAAGGAAAACAGAACTGACCACTGCTGACTGGGAAGCCCACATCCCTCCACACTTACCCAAAG
Downstream sequence
GATCTTAccagccgggaggccctccctggtctccagggcacacttctcttctgtgaagacctctatcatgcactacactgcattgtaattgcttacatat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate