Basic Information
VIS ID
TVIS30009228
Fusion event
HIV-EIF3B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
2411598/2371963 (Hg38)
End
2411598/2371963 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
EIF3B
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-423-3p ; hsa-mir-324-3p ; hsa-mir-151a-3p ; hsa-mir-222-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-339/Upstream/114386; hsa-mir-10399/Downstream/155111;
Nearest TSS
ENST00000635602/Upstream/5433; ENST00000494658/Downstream/1155;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/16424, chr7-CpG: 39/Downstream/8210
Upstream sequence
AGTCACTTTGAGGCGAATGGGGCCTACGTGCTGTTTTACTCTTGGCTTTAACACTTCCATGCGAGGGGTTGTCTGAGCAGCTGAGTCAGGACTGTGAGCC
Downstream sequence
CTCACCATGAATAGTCATCTCCAGGTCACAGAACGTGTTTAGagcctgggcaacatagtgagaccctctctgtacaaaaaacaaataaaaaaaattagcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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