Basic Information
VIS ID
TVIS30009233
Fusion event
HIV-WIPI2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
5237701/5198070 (Hg38)
End
5237701/5198070 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
WIPI2
miRNAs that regulate target gene
hsa-mir-505-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-3908 ; hsa-mir-3909 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6507-3p ; hsa-mir-6780a-3p ; hsa-mir-6838-5p ; hsa-mir-6852-3p ; hsa-mir-3611 ; hsa-mir-7843-3p ; hsa-mir-4786-3p ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-103b ; hsa-mir-646 ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-503-5p ; hsa-mir-575 ; hsa-mir-4676-5p
Nearest miRNA
hsa-mir-339/Upstream/409431; hsa-mir-10399/Downstream/297749;
Nearest TSS
ENST00000635602/Upstream/7377; ENST00000475309/Downstream/16116;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/7360, chr7-CpG: 28/Downstream/29220
Upstream sequence
ATGAGGAAACCCCTTCTGTGGTGTCCCCGAGGCCCCTGCTGGGAGGGGCTGCTGAGCTGTGGGCTCCTTGAGCCTCCTCGCAGAAGCGGGTGATGAGTAT
Downstream sequence
GGACTCATAAACGCAAGGCCATGAAACCAATCCTCTGCTTTTTCCTTGTAAGCCAACGACGGGGCCTTTGATTCCAGACTCTAAGGTAGCTTTGGAGTCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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