Basic Information
VIS ID
TVIS30009264
Fusion event
HIV-OSBPL3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
24975178/24935559 (Hg38)
End
24975178/24935559 (Hg38)
Orient
+
Location type
Intronic
Target gene
OSBPL3
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-4662a-5p ; hsa-mir-3151-3p ; hsa-mir-6890-3p ; hsa-mir-3163 ; hsa-mir-449b-3p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-6499-3p ; hsa-mir-539-5p ; hsa-mir-6838-5p ; hsa-mir-4519 ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-548e-5p ; hsa-mir-4712-3p ; hsa-mir-4757-3p ; hsa-mir-4517 ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-1183/Upstream/3464413; hsa-mir-10399/Downstream/1014360;
Nearest TSS
ENST00000635602/Upstream/17466; ENST00000607375/Downstream/44629;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/177691, chr7-CpG: 134/Downstream/43821
Upstream sequence
cgccaccacaaacaagatacagaattgtccatcaccacagagaAAACTacaagggaactttttacactactagaaatggtctatatcttgacctgggtgg
Downstream sequence
tggttaGGCCATATACTTCAGTTATACAATTTAGATTATAAAGTATGCTTATATCTAAAAAGAATGATGAAAAGTTCTATTGATTGATGGCACATTAGGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate