Basic Information
VIS ID
TVIS30009327
Fusion event
HIV-ZNF736 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
63776271/64315893 (Hg38)
End
63776271/64315893 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
ZNF736
miRNAs that regulate target gene
hsa-mir-4291 ; hsa-mir-3926 ; hsa-mir-7157-5p ; hsa-mir-5680 ; hsa-mir-4310 ; hsa-mir-4753-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-151a-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-4277 ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-4524b-3p ; hsa-mir-494-3p ; hsa-mir-892c-5p ; hsa-mir-570-3p ; hsa-mir-873-5p ; hsa-mir-1207-3p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p
Nearest miRNA
hsa-mir-1183/Upstream/694724; hsa-mir-10399/Downstream/363171;
Nearest TSS
ENST00000635602/Upstream/1864; ENST00000360117/Downstream/228326;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8280, chr7-CpG: 24/Downstream/148129
Upstream sequence
CATTCCCAAATGCCAACTATCCCTCTCCAAATCACATTATGAACTATCAGTTCTTTATTTAATTTTAAAACGGATGTGGCATTTTGTTTATTTTTGTTTA
Downstream sequence
ACAGAGCCGTGGGTGGCTCTTTTTAATATATTAGTCTGTTTGTGCATATTTCACAGGACAGAAAAGCAAAGAGTAGTCACCTGACACTGCGCATCTCCTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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