Basic Information
VIS ID
TVIS30009337
Fusion event
HIV-MLXIPL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
73026613/73612283 (Hg38)
End
73026613/73612283 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
MLXIPL
miRNAs that regulate target gene
hsa-mir-6894-3p ; hsa-mir-4763-5p ; hsa-mir-1322 ; hsa-mir-4643 ; hsa-mir-8485 ; hsa-mir-3692-3p ; hsa-mir-6881-3p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5196-3p ; hsa-mir-18a-3p
Nearest miRNA
hsa-mir-1183/Upstream/914305; hsa-mir-10399/Downstream/99034;
Nearest TSS
ENST00000635602/Upstream/5163; ENST00000324941/Downstream/3878;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/4893, chr7-CpG: 116/Downstream/10915
Upstream sequence
agctgggtgtgggggcgcatgcctgtagtcccagctactagggaggccgaggtgggggaattgcttgagcccaggaattggaggccgcagtgagctatgt
Downstream sequence
tggctccactgcactccagcctgggtgatgaagtgagaccctgtctcaaaaaatagaataaaaTTAAGTTTGTTAggccaggcgcggtggctcacgcctg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate