Basic Information
VIS ID
TVIS30009364
Fusion event
HIV-SEM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
96322104/96692792 (Hg38)
End
96322104/96692792 (Hg38)
Orient
-
Location type
Intronic
Target gene
SEM1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-30c-5p ; hsa-mir-599 ; hsa-mir-653-5p ; hsa-mir-3161 ; hsa-mir-6807-5p ; hsa-mir-526b-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p
Nearest miRNA
hsa-mir-10525/Upstream/473036; hsa-mir-10399/Downstream/1270866;
Nearest TSS
ENST00000635602/Upstream/28454; ENST00000555308/Downstream/4580;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/370468, chr7-CpG: 38/Downstream/16712
Upstream sequence
aaagagcaggtacaatgcttggaacagatgatgtaacattaacagattttagagaaaaagcaggattattgttcaatagctatcatttttatcttgtcca
Downstream sequence
taaaactataaaaggaaaaacaacataattaagacaaaattgaaaactaagacaggtaagataactgcattaaggcagtttaaaatctcaaggctctgga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate