Basic Information
VIS ID
TVIS30009385
Fusion event
HIV-PMPCB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
102944115/103303668 (Hg38)
End
102944115/103303668 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
PMPCB
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-10525/Upstream/832137; hsa-mir-10399/Downstream/11349677;
Nearest TSS
ENST00000635602/Upstream/6211; ENST00000469560/Downstream/6910;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/22601, chr7-CpG: 40/Downstream/40742
Upstream sequence
AAATTTCCATAGCATTTTTTAAGTAGGTAGAGTCATTACAAGGTGATGGCAAATTTATACTTTTTCCCCAAGGAAAAAATCTTTTGTACTATAGGGGTTT
Downstream sequence
ATATGTTAAATTTTAATTTTGTCCTGTTAAGTATATCTGATGTTTTTCTCCTAGGCTAATCATTTAGTATTGAGTGATGGGTCAGTGTCATGATTTCTGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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