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TVIS30009421
Basic Information
VIS ID
TVIS30009421
Fusion event
HIV-MKLN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
131057661/131372902 (Hg38)
End
131057661/131372902 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7H
Target gene
MKLN1
miRNAs that regulate target gene
hsa-mir-128-3p
;
hsa-mir-124-3p
;
hsa-mir-101-3p
;
hsa-mir-27a-3p
;
hsa-mir-320b
;
hsa-mir-324-5p
;
hsa-mir-100-5p
;
hsa-mir-142-3p
;
hsa-mir-16-1-3p
;
hsa-mir-144-3p
;
hsa-mir-376c-5p
;
hsa-mir-376b-5p
;
hsa-mir-513a-5p
;
hsa-mir-651-3p
;
hsa-mir-1252-5p
;
hsa-mir-3165
;
hsa-mir-5002-5p
;
hsa-mir-6880-5p
;
hsa-mir-8071
;
hsa-mir-142-5p
;
hsa-mir-5590-3p
;
hsa-mir-4496
;
hsa-mir-511-3p
;
hsa-mir-297
;
hsa-mir-3924
;
hsa-mir-155-5p
;
hsa-mir-5191
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-3154
;
hsa-mir-223-5p
;
hsa-mir-567
;
hsa-mir-340-5p
;
hsa-mir-8054
;
hsa-mir-548l
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548b-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-548c-3p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-6805-3p
;
hsa-mir-5691
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-3194-3p
;
hsa-mir-6499-3p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-6733-3p
;
hsa-mir-143-5p
;
hsa-mir-106a-3p
;
hsa-mir-8055
;
hsa-mir-374b-3p
;
hsa-mir-539-3p
;
hsa-mir-485-3p
;
hsa-mir-889-3p
;
hsa-mir-548au-3p
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-34a-5p
;
hsa-mir-3140-3p
;
hsa-mir-4686
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-3529-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
Nearest miRNA
hsa-mir-10525/Upstream/495363; hsa-mir-10399/Downstream/1661958;
Nearest TSS
ENST00000635602/Upstream/45005;
ENST00000497746/Downstream/90374;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/44471
,
chr7-CpG: 106/Downstream/182852
Upstream sequence
actttgtagactgactgccttgggttcaaatccttacttagctgtatacgtttaggcaattaatcttttctttttctttttctttcttttctttctttgc
Downstream sequence
tcccttccctaccttctttcttttcttttttctttTACCTTTTTCCTGCAGTATGTTTCAATTTCTTAAATTTGTATACTTCCAAGATAATGGTTTATAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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