Basic Information
VIS ID
TVIS30009435
Fusion event
HIV-AGK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
141295877/141596077 (Hg38)
End
141295877/141596077 (Hg38)
Orient
+
Location type
Intronic
Target gene
AGK
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-378a-3p ; hsa-mir-526b-5p ; hsa-mir-3682-3p ; hsa-mir-5571-5p ; hsa-mir-6734-5p ; hsa-mir-629-3p ; hsa-mir-6834-5p ; hsa-mir-1226-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-582-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6875-5p ; hsa-mir-4419a ; hsa-mir-5695 ; hsa-mir-3126-5p ; hsa-mir-519d-5p ; hsa-mir-3691-3p
Nearest miRNA
hsa-mir-10399/Upstream/2551920; hsa-mir-11400/Downstream/878450;
Nearest TSS
ENST00000635602/Upstream/40611; ENST00000496273/Downstream/5144;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/44405, chr7-CpG: 81/Downstream/105555
Upstream sequence
agaataatgtgtgtaaaaatgtcaaataaaaggtgcttggtatatattaGTTATGTTTCTTTTCCCCTGCCAGTTGCTGCTATTTAGTTATCATACAGGG
Downstream sequence
TTGCAAAGAAGAGAAGGCAAATAGAGTATTCGGTTTATTTTGTATGTGTGTAAACATATGAAGATTAACTGGTAACACAAAGATTCTTCATGAACAAATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate