Basic Information
VIS ID
TVIS30009445
Fusion event
HIV-ZNF746 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
149177192/149480101 (Hg38)
End
149177192/149480101 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
ZNF746
miRNAs that regulate target gene
hsa-mir-326 ; hsa-let-7d-5p ; hsa-let-7a-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-5093 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-320e
Nearest miRNA
hsa-mir-10399/Upstream/2101980; hsa-mir-153-2/Downstream/1758320;
Nearest TSS
ENST00000635602/Upstream/2229; ENST00000486744/Downstream/17632;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/5114, chr7-CpG: 140/Downstream/16947
Upstream sequence
catcccctgtggtcccagctactcaggaggcCCATTgtggcccaaaaacttccaggtcaagactgtagcttgaagtggtcctaagtctgcattggcatca
Downstream sequence
gatgaccagctgaggaacacacacacattctcaggaggaaagcattttaaacatagctttcaaataatcaatgagctcacaattacacatcaccatctcg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate