Basic Information
VIS ID
TVIS30009474
Fusion event
HIV-ANGPT2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
6358492/6500971 (Hg38)
End
6358492/6500971 (Hg38)
Orient
+
Location type
UTR3
Target gene
ANGPT2
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-542-3p ; hsa-mir-125b-5p
Nearest miRNA
hsa-mir-3674/Upstream/4424331; hsa-mir-10400/Downstream/121153;
Nearest TSS
ENST00000518652/Upstream/23612; ENST00000521175/Downstream/62073;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/94170, chr8-CpG: 53/Downstream/65723
Upstream sequence
TCACCTGCCTACAAAGAGAATTGATATAAATTGTGTTGTTGCCAGTTTTTCCTGCATTAGCGTTTCCCTACCTAAGTATCCATCACTCTTGTCATTGAGA
Downstream sequence
TATCCTAGAAACTTGTTGTTGTCTTTCGAGGCTGTGAAATTTTCTTATTTTCAGTTGTTTTTCAACTTGATACAAGGCCATGATACCGTTGTTGAATTCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate