Basic Information
VIS ID
TVIS30009491
Fusion event
HIV-XPO7 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
21820809/21963298 (Hg38)
End
21820809/21963298 (Hg38)
Orient
-
Location type
Intronic
Target gene
XPO7
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-186-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-30a-5p ; hsa-mir-6844 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-5702
Nearest miRNA
hsa-mir-124-1/Upstream/4281641; hsa-mir-10400/Downstream/281668;
Nearest TSS
ENST00000518652/Upstream/41842; ENST00000518808/Downstream/2940;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/42867, chr8-CpG: 43/Downstream/46923
Upstream sequence
TCATCTCAGATGGCTGGGTGGCAGTCAGGTTAAGAATGTGCTCTTCAGAACACCTGCGGATCTGACTGGTCACCCAAGGATTATGCTTATGTCTAGTTCA
Downstream sequence
GTACTCAATATTATTGGGAGTGTCATTGACTCCTTCCTAAAAGCAAGAATCGTAGTCTGTGATTGGAACTCTCCATGCGGATTTTTTAAAGCAGTGAGGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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