Basic Information
VIS ID
TVIS30009492
Fusion event
HIV-PIWIL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
22133506/22275993 (Hg38)
End
22133506/22275993 (Hg38)
Orient
+
Location type
UTR5
Target gene
PIWIL2
miRNAs that regulate target gene
hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4795-5p ; hsa-mir-4775 ; hsa-mir-93-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-455-5p ; hsa-mir-590-3p ; hsa-mir-8485 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6888-3p ; hsa-mir-452-3p ; hsa-mir-3120-5p
Nearest miRNA
hsa-mir-124-1/Upstream/30956; hsa-mir-10400/Downstream/2677803;
Nearest TSS
ENST00000518652/Upstream/426; ENST00000611073/Downstream/3369;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/149, chr8-CpG: 83/Downstream/91013
Nearest cancer related gene
PIWIL2(TSG, No orient, 0)
Upstream sequence
GGGGAAACCCACACTGGGAGAGGGCCCTCTGGGGGAGCTACCTGAATCTATAGAAGTGGTGCTGGAGGTTGAGGGAAGCGTGGACAAAGAGGAAGATTCC
Downstream sequence
AGATGTCCCTTAAGGGAGGCCGTCCAGCGCTTCTGAGTATGTAGCTGTTAGCATACTGATTGCTTGGGATTCTTTGGGTGGTGTTGGGGAGGTGTGAGCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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