Basic Information
VIS ID
TVIS30009495
Fusion event
HIV-PPP3CC integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
22379950/22522437 (Hg38)
End
22379950/22522437 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPP3CC
miRNAs that regulate target gene
hsa-mir-6086 ; hsa-mir-6851-3p ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-6832-3p ; hsa-mir-3922-5p
Nearest miRNA
hsa-mir-124-1/Upstream/277400; hsa-mir-10400/Downstream/2431359;
Nearest TSS
ENST00000518652/Upstream/11529; ENST00000523941/Downstream/22549;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/80808, chr8-CpG: 107/Downstream/28722
Nearest cancer related gene
PPP3CC(TSG, No orient, 0)
Upstream sequence
GATGAGTACTAAGCTATTCATAAAATTTCAGTAGTGTGTAATACTTGTAGTTTTGAAACAAAATCAGCTAATATCACCTTGACTTTTCCCCATCTTCCTA
Downstream sequence
TTAAAAAAAATTGTTTTAATTCTGGATTTATGTTTTCTAATTTTCTTTTCCAGTTACCCTGCAGTTTGTGAATTTTTGCAGAACAATAATTTACTATCAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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