Basic Information
VIS ID
TVIS30009504
Fusion event
HIV-DOCK5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
25057129/25199613 (Hg38)
End
25057129/25199613 (Hg38)
Orient
-
Location type
Intronic
Target gene
DOCK5
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-21-5p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-93-3p ; hsa-mir-222-3p ; hsa-mir-4762-5p ; hsa-mir-4719 ; hsa-mir-513b-3p
Nearest miRNA
hsa-mir-124-1/Upstream/245746; hsa-mir-10400/Downstream/145789;
Nearest TSS
ENST00000518652/Upstream/14748; ENST00000495236/Downstream/96969;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/14308, chr8-CpG: 134/Downstream/258157
Upstream sequence
gctgggattataagcatttgccaccacacccggctaatttttgtattttagtagagacggggtttcaccatgttggccaagctggtcttgaactcctgac
Downstream sequence
ctcaggtgatcctcccgccttggcctcccaaagtgttgggattacatgcgtgagccaccacgcccaaccAACTTCTGCTCTATTTTCTTTGCTGGGAGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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