Basic Information
VIS ID
TVIS30009516
Fusion event
HIV-LEPROTL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
29963300/30105784 (Hg38)
End
29963300/30105784 (Hg38)
Orient
+
Location type
Exonic
Target gene
LEPROTL1
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-375 ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-15a-3p ; hsa-mir-149-5p ; hsa-mir-100-3p ; hsa-mir-595 ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4423-5p ; hsa-mir-656-5p ; hsa-mir-1255b-2-3p ; hsa-mir-496 ; hsa-mir-3670 ; hsa-mir-6854-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-6727-5p ; hsa-mir-7977 ; hsa-mir-4508 ; hsa-mir-6775-5p ; hsa-mir-5090 ; hsa-mir-383-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-520h ; hsa-mir-520g-3p
Nearest miRNA
hsa-mir-124-1/Upstream/148436; hsa-mir-10400/Downstream/11165264;
Nearest TSS
ENST00000518652/Upstream/3844; ENST00000522540/Downstream/38902;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/9716, chr8-CpG: 48/Downstream/50400
Upstream sequence
TTTTTTTTTATTTTCCTTTCGTTTTTCATGCCTGTTGACTGAGTGTATCTTATTTCCATAGATTGAGTGGGGAGCTTGTGCACTTGTTCTCACAGGAAAC
Downstream sequence
ACAGTCATCTTTGCAACTATACTAGGCTTTTTCTTGGTCTTTGGAAGCAATGACGACTTCAGCTGGCAGCAGTGGTGAAAAGAAATTACTGAACTATTGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate