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VISDB
Viral Integration Site DataBase
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TVIS30009520
Basic Information
VIS ID
TVIS30009520
Fusion event
HIV-WRN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
GRCh37/hg19
Start
30981157/31123641 (Hg38)
End
30981157/31123641 (Hg38)
Orient
+
Location type
Intronic
Target gene
WRN
miRNAs that regulate target gene
hsa-mir-592
;
hsa-mir-597-5p
;
hsa-mir-3681-3p
;
hsa-mir-4717-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-4748
;
hsa-mir-329-5p
;
hsa-mir-4464
;
hsa-mir-3664-5p
;
hsa-mir-144-3p
;
hsa-mir-224-5p
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-4533
;
hsa-mir-1252-5p
;
hsa-mir-3185
;
hsa-mir-4476
;
hsa-mir-6876-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4709-3p
;
hsa-mir-6077
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
;
hsa-mir-5197-3p
;
hsa-mir-4311
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-4310
;
hsa-mir-7157-5p
;
hsa-mir-3617-3p
;
hsa-mir-216b-5p
;
hsa-mir-5089-5p
;
hsa-mir-4423-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-500b-3p
;
hsa-mir-1295b-3p
;
hsa-mir-3622a-5p
;
hsa-mir-5582-5p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-7847-3p
;
hsa-mir-6894-5p
;
hsa-mir-7154-3p
;
hsa-mir-3928-3p
;
hsa-mir-5003-3p
Nearest miRNA
hsa-mir-124-1/Upstream/1166293; hsa-mir-10400/Downstream/10147407;
Nearest TSS
ENST00000518652/Upstream/3685;
ENST00000524022/Downstream/53231;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/89932
,
chr8-CpG: 142/Downstream/515368
Upstream sequence
AACGGATCATTTGTGTCTTCAGACTTTCCAGAACTCCTTGAGAATTATGCAGAGGTATTTAATCAGTCAGAAGGTTGAATAGTCAAATTATTAGTGAGTG
Downstream sequence
AAGTCTATTTTGATGAGGATTTTACTAATGCTGTCCCTTAGATATTATAAGTAAATCGTTGTTTTCTTTTGAAATATCTGAAACCTAGTTAACATGGACT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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