Basic Information
VIS ID
TVIS30009535
Fusion event
HIV-KAT6A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
41886474/42028956 (Hg38)
End
41886474/42028956 (Hg38)
Orient
-
Location type
Intronic
Target gene
KAT6A
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-21-5p ; hsa-mir-877-3p ; hsa-mir-296-3p ; hsa-mir-193b-3p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-576-5p ; hsa-mir-6867-5p ; hsa-mir-3134 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-511-3p ; hsa-mir-580-5p ; hsa-mir-574-5p ; hsa-mir-6505-5p ; hsa-mir-2681-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-223-5p
Nearest miRNA
hsa-mir-124-1/Upstream/368448; hsa-mir-10400/Downstream/867241;
Nearest TSS
ENST00000518652/Upstream/51466; ENST00000521235/Downstream/23031;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/131224, chr8-CpG: 183/Downstream/21899
Nearest cancer related gene
KAT6A(OG, No orient, 0)
Upstream sequence
ttctctttttcatttgtatgtctgctcttctagtgagttttatgtatttgcatgttttcatggcggtacatattgccctttcactttcagatttagaact
Downstream sequence
cccttaagcatttcttgtagggccatctagtgttgataaattcccttgatttttttcttatctgggaaagaatttatttatctttcattctaaaaagaca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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