Basic Information
VIS ID
TVIS30009561
Fusion event
HIV-NCOA2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
71178115/70265880 (Hg38)
End
71178115/70265880 (Hg38)
Orient
-
Location type
Intronic
Target gene
NCOA2
miRNAs that regulate target gene
hsa-mir-137 ; hsa-mir-193b-3p ; hsa-mir-544a ; hsa-mir-1185-5p ; hsa-mir-6864-5p ; hsa-mir-4471 ; hsa-mir-8059 ; hsa-mir-539-5p ; hsa-mir-3179 ; hsa-mir-7515 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-3120-3p ; hsa-mir-429 ; hsa-mir-200b-3p ; hsa-mir-200c-3p
Nearest miRNA
hsa-mir-124-1/Upstream/5886623; hsa-mir-10400/Downstream/4282663;
Nearest TSS
ENST00000518652/Upstream/20505; ENST00000520259/Downstream/136199;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/193227, chr8-CpG: 251/Downstream/136030
Upstream sequence
TGTACCAAGAGCAAACCAGAAACTTCAGTTTTttgttgttgttgttgttgttgttttgttTGTTTTTTTAAAGAGACAGAGTCggctgggcgtggtggct
Downstream sequence
cacgcctgtaatcccagcactttgggaggctgagggatcacgagatcaagaatttgagaccagcctggccaatatggtgtaaccccgtctctaatacaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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