Basic Information
VIS ID
TVIS30009565
Fusion event
HIV-UBE2W integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
74740166/73827931 (Hg38)
End
74740166/73827931 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2W
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-128-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-mir-218-5p ; hsa-mir-382-3p ; hsa-mir-5692a ; hsa-mir-548c-3p ; hsa-mir-3185 ; hsa-mir-141-5p ; hsa-mir-5197-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-431-5p ; hsa-mir-3120-5p ; hsa-mir-4760-3p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-124-1/Upstream/9448674; hsa-mir-10400/Downstream/720612;
Nearest TSS
ENST00000518652/Upstream/80223; ENST00000523794/Downstream/2543;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/80338, chr8-CpG: 109/Downstream/50176
Upstream sequence
accatgccaggACTAATAAGTTTGTATTAGttaaaaaagttaagatatgttcattgtagaaacttcagaaaagtataaacaaaaatcacccagtgataac
Downstream sequence
cactgttaaagtttttgggggtatatttcattctagtcattttgctGTTTCCTATACCATCGAAGCCTATATGAAATGGCAGCCCAGTAGCTGCATTTTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate