Basic Information
VIS ID
TVIS30009568
Fusion event
HIV-ZFHX4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
77681793/76769557 (Hg38)
End
77681793/76769557 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZFHX4
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-mir-128-3p ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-19b-3p ; hsa-let-7b-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-200b-3p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-200c-3p ; hsa-mir-369-3p ; hsa-mir-424-5p ; hsa-mir-429 ; hsa-mir-409-3p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-8084 ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-5003-3p ; hsa-mir-646 ; hsa-mir-503-5p
Nearest miRNA
hsa-mir-124-1/Upstream/2063810; hsa-mir-10400/Downstream/197211;
Nearest TSS
ENST00000518652/Upstream/65512; ENST00000524290/Downstream/8725;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/86932, chr8-CpG: 78/Downstream/230339
Upstream sequence
tcctacttcagcctcaccagtagctaggactacaggcaatgagtcactatgcctggctaatttttgtattttttgtagatacaggagtttgccatattag
Downstream sequence
cccaggctggtcttgaattcctgggctcaagccatctgcctgcctcagcctcccaaagtgctaggatcataggcgtgagccatgtcacacagccTAGAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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