Basic Information
VIS ID
TVIS30009575
Fusion event
HIV-E2F5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
86097209/85184974 (Hg38)
End
86097209/85184974 (Hg38)
Orient
+
Location type
Intronic
Target gene
E2F5
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-124-3p ; hsa-mir-205-5p ; hsa-let-7b-5p ; hsa-mir-192-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-378a-3p ; hsa-mir-106b-5p ; hsa-mir-181a-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-let-7c-5p ; hsa-mir-98-5p ; hsa-mir-98-3p ; hsa-mir-154-5p ; hsa-mir-1233-3p ; hsa-mir-129-1-3p ; hsa-mir-129-2-3p ; hsa-mir-218-2-3p ; hsa-mir-584-5p ; hsa-mir-6501-3p ; hsa-mir-758-5p
Nearest miRNA
hsa-mir-12123/Upstream/4943501; hsa-mir-10400/Downstream/6020511;
Nearest TSS
ENST00000518652/Upstream/6824; ENST00000521234/Downstream/2711;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6922, chr8-CpG: 42/Downstream/35218
Nearest cancer related gene
E2F5(OG, No orient, 0)
Upstream sequence
atggaaaaacattctatgctcatggataggaagaatcaatatcatgaacatggccatactgcccaaagtaatttatagattcaatgctatccctatcaag
Downstream sequence
ctaccaatgactttcttcacagaattggaaaaaactacttcaaacttcatagggaaccaaaaaagagcctgcatagccaagacaatcttaagcaaaaata
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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