Basic Information
VIS ID
TVIS30009583
Fusion event
HIV-NDUFAF6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95931257/94919029 (Hg38)
End
95931257/94919029 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
NDUFAF6
miRNAs that regulate target gene
hsa-mir-3679-3p ; hsa-mir-6807-5p ; hsa-mir-6868-3p ; hsa-mir-6826-3p ; hsa-mir-2355-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-3124-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p
Nearest miRNA
hsa-mir-12123/Upstream/1002910; hsa-mir-10400/Downstream/153882;
Nearest TSS
ENST00000518652/Upstream/22351; ENST00000521587/Downstream/30337;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/22169, chr8-CpG: 165/Downstream/29494
Nearby gene
TP53INP1(No orient, 6943)
Upstream sequence
TAGGCCACGGTGTATTGAAGCAACTTTGGGACACATTCTCTTTAGCCAGATAATTCAATGGCAAAAAAACTTGAAAAACTTAAGTTTTATTCTTGTTATA
Downstream sequence
GAGGAAGCAAATTCCTCACTTCTTTTAGGACTATCTTTTGAAATACATGTTATTTCCAGCTTAAAGAACTTAGAAATAAAATCTTACCCCAATAGATGAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate