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Viral Integration Site DataBase
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TVIS30009586
Basic Information
VIS ID
TVIS30009586
Fusion event
HIV-MTDH integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
98695518/97683290 (Hg38)
End
98695518/97683290 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
MTDH
miRNAs that regulate target gene
hsa-mir-26a-5p
;
hsa-mir-375
;
hsa-mir-136-5p
;
hsa-mir-215-5p
;
hsa-mir-34a-5p
;
hsa-mir-192-5p
;
hsa-mir-30a-5p
;
hsa-mir-139-3p
;
hsa-mir-30c-5p
;
hsa-mir-542-3p
;
hsa-mir-34b-5p
;
hsa-mir-378a-5p
;
hsa-mir-545-5p
;
hsa-mir-449c-5p
;
hsa-mir-1200
;
hsa-mir-2682-5p
;
hsa-mir-3714
;
hsa-mir-140-3p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30e-5p
;
hsa-mir-26b-5p
;
hsa-mir-1297
;
hsa-mir-4465
;
hsa-mir-499a-5p
;
hsa-mir-137
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-1273e
;
hsa-mir-937-5p
;
hsa-mir-6894-5p
;
hsa-mir-5702
;
hsa-mir-6840-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-630
;
hsa-mir-552-3p
;
hsa-mir-3910
;
hsa-mir-506-3p
;
hsa-mir-124-3p
;
hsa-mir-5697
;
hsa-mir-4432
;
hsa-mir-8087
;
hsa-mir-653-5p
;
hsa-mir-549a
;
hsa-mir-6719-3p
;
hsa-mir-4526
;
hsa-mir-3660
;
hsa-mir-892c-3p
;
hsa-mir-4676-3p
;
hsa-mir-452-5p
;
hsa-mir-429
;
hsa-mir-200c-3p
;
hsa-mir-200b-3p
;
hsa-mir-506-5p
;
hsa-mir-320a
;
hsa-mir-302c-3p
;
hsa-mir-145-5p
;
hsa-mir-145-3p
;
hsa-mir-153-3p
;
hsa-mir-342-3p
;
hsa-mir-22-3p
;
hsa-mir-217
;
hsa-mir-4738-3p
;
hsa-mir-548g-3p
;
hsa-mir-619-5p
;
hsa-mir-6807-5p
Nearest miRNA
hsa-mir-12123/Upstream/2610294; hsa-mir-10400/Downstream/710355;
Nearest TSS
ENST00000518652/Upstream/38497;
ENST00000522104/Downstream/7729;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/38288
,
chr8-CpG: 107/Downstream/92317
Nearest cancer related gene
MTDH
(OG, No orient, 0)
Upstream sequence
agtagctgggactacaggcacgtgccaccacacctggctaattttttgtatttttagtagagatgggtttcaccatgttagccaggatggtctcgatctc
Downstream sequence
ctaagctcaggatctgcccgcctcagcctcccaaagtgctggggttacaggcgtgagccaccacgcccagccTCTTAGACACTTTTCTTTGttttttgtt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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