Basic Information
VIS ID
TVIS30009602
Fusion event
HIV-EIF3E integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
109247282/108235053 (Hg38)
End
109247282/108235053 (Hg38)
Orient
+
Location type
Exonic
Target gene
EIF3E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-29a-3p ; hsa-mir-218-5p ; hsa-mir-335-3p ; hsa-mir-452-3p
Nearest miRNA
hsa-mir-12123/Upstream/3750588; hsa-mir-10400/Downstream/4408440;
Nearest TSS
ENST00000518652/Upstream/3145; ENST00000524143/Downstream/7780;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/151432, chr8-CpG: 43/Downstream/13244
Nearest cancer related gene
EIF3E(OG, No orient, 0)
Upstream sequence
aaaagacaaaaaaaaaaaaaaaaaaaaCATGTACTTATACTTACCAGCACTCTAAAAAAATAAAGATATTCTGCTGCTCCTGAGTAATTCCCACATTCGT
Downstream sequence
ACTGGAATTTTGCATATCTGTAGAGTGTATCTAAATATTCCTGCCTAAACTAAAAAGAAAAAAAAAAGATTAAGTTCTCTTTAATTTAGAGTTTTAAAAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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