Basic Information
VIS ID
TVIS30009624
Fusion event
HIV-FAM91A1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
124821360/123809120 (Hg38)
End
124821360/123809120 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
FAM91A1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-106b-5p ; hsa-mir-125b-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-548e-5p ; hsa-mir-595 ; hsa-mir-1910-3p ; hsa-mir-3658 ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-6511a-5p ; hsa-mir-3653-3p ; hsa-mir-6885-3p ; hsa-mir-4639-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-520f-5p ; hsa-mir-6796-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-12123/Upstream/460990; hsa-mir-10400/Downstream/699395;
Nearest TSS
ENST00000518652/Upstream/191; ENST00000522917/Downstream/42867;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/40095, chr8-CpG: 34/Downstream/492322
Upstream sequence
GGGTTTATATTCGCTGTCATATTTTCATATCAATTTTTAAGCTGTCAGCAAATAGTTACCATATCTTACTTTTATTCCACACATGAGCACAGTAATTGTT
Downstream sequence
CTGTATATATTTGTTGATTGAATAGAGATCGCTAGTTTAAGGGTTTTGCTGTATTTTTCAAAATTAAATTTCACTAGATCAGAAATTAGTCACAGGCAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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