Basic Information
VIS ID
TVIS30009637
Fusion event
HIV-PVT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
129047412/128035166 (Hg38)
End
129047412/128035166 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
PVT1
miRNAs that regulate target gene
hsa-mir-186-5p
Nearest miRNA
hsa-mir-1204/Upstream/26210; hsa-mir-10400/Downstream/13986;
Nearest TSS
ENST00000518652/Upstream/25508; ENST00000616386/Downstream/34994;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/185188, chr8-CpG: 122/Downstream/1903960
Nearest cancer related gene
PVT1(OG, No orient, 0)
Upstream sequence
AAAAGCATTTGTGGCAAGGATCCAGTTATTTGCAGGCTTCTCTTCTGTCTGGCTTTGTTTACTGTCATGCAGGAAAAGTGCCTTCACCAGGGCACAGCAG
Downstream sequence
TAAACCTGTTGGCTACTCTAGTCCTGCCTGGGTTCCCAGGAAATTGGCATGAGAGGAGCTGCCTGCTGCTTGTGGGCCTGCTATTTAGGCTGCAATAGCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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