Basic Information
VIS ID
TVIS30009666
Fusion event
HIV-MROH1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145280278/144225375 (Hg38)
End
145280278/144225375 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
MROH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-222-3p ; hsa-mir-1273h-3p ; hsa-mir-3166 ; hsa-mir-3929 ; hsa-mir-4251 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4768-3p ; hsa-mir-4771 ; hsa-mir-485-5p ; hsa-mir-6884-5p
Nearest miRNA
hsa-mir-1204/Upstream/145433; hsa-mir-10400/Downstream/37298;
Nearest TSS
ENST00000518652/Upstream/26256; ENST00000528664/Downstream/13737;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/22001, chr8-CpG: 19/Downstream/13272
Upstream sequence
tgggcacaagtcctttgttggatttatggcttataaatatGTATTTTTTTAACTTTTAATACATATTGttttgttcttgaatagagacagcctgtgttac
Downstream sequence
ccaggctgatctttaactcttggccttgagtgatttgcttgcctcagcctcccaaagtgctgggattatacgtatgggcctctgctcctgcccATagaca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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