Basic Information
VIS ID
TVIS30009676
Fusion event
HIV-ZNF251 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145977341/144751956 (Hg38)
End
145977341/144751956 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
ZNF251
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1233-5p ; hsa-mir-1298-3p ; hsa-mir-185-5p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3165 ; hsa-mir-4306 ; hsa-mir-452-3p ; hsa-mir-4644 ; hsa-mir-4667-5p ; hsa-mir-4700-5p ; hsa-mir-5192 ; hsa-mir-541-3p ; hsa-mir-6134 ; hsa-mir-637 ; hsa-mir-654-5p ; hsa-mir-6731-5p ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6778-5p ; hsa-mir-6788-5p ; hsa-mir-6803-5p ; hsa-mir-6835-5p ; hsa-mir-6842-5p ; hsa-mir-6878-5p ; hsa-mir-6880-5p ; hsa-mir-7110-5p ; hsa-mir-7155-5p ; hsa-mir-8071 ; hsa-mir-8085 ; hsa-mir-8089 ; hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-10400/Upstream/289417; hsa-mir-6850/Downstream/39975;
Nearest TSS
ENST00000518652/Upstream/38057; ENST00000528012/Downstream/3485;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/21352, chr8-CpG: 72/Downstream/3191
Upstream sequence
tgaaagaagatatactatgctaacagtaagtataagaaggatggaattgctacattaatattagataaaatatatttcaaaacaaaatgtattaccagag
Downstream sequence
acaaacaggaattctcttatctctcataatgatagtcataagtgaagtaagtcttataatacagcttcaagatacatgaagccaacactacaaaaattaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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