Basic Information
VIS ID
TVIS30009690
Fusion event
HIV-UHRF2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
6415869/6415869 (Hg38)
End
6415869/6415869 (Hg38)
Orient
+
Location type
Intronic
Target gene
UHRF2
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-335-5p ; hsa-mir-30a-5p ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-101-2/Upstream/407965; hsa-let-7a-1/Downstream/12157437;
Nearest TSS
ENST00000422679/Upstream/1811; ENST00000450508/Downstream/5162;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1772, chr9-CpG: 63/Downstream/229211
Nearest cancer related gene
UHRF2(TSG, No orient, 0)
Upstream sequence
TTCAGCTCACCCCAGAACTGCAAGTAGTTGAATTTAACAAGACCCCACGGGAGATTCTGATAACACCAGAGTTTAGAAAATGAATGTTGATAGATAGTCT
Downstream sequence
CCCACTAGTCTcttactattcaaagtatggtccctggattctcaggaccagcagcattagctttacctgaaatcctcacgccagacctactgaagctgac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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