Basic Information
VIS ID
TVIS30009691
Fusion event
HIV-UHRF2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
6460591/6460591 (Hg38)
End
6460591/6460591 (Hg38)
Orient
-
Location type
Exonic
Target gene
UHRF2
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-335-5p ; hsa-mir-30a-5p ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-101-2/Upstream/452687; hsa-let-7a-1/Downstream/12112715;
Nearest TSS
ENST00000422679/Upstream/11033; ENST00000477183/Downstream/21460;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/46494, chr9-CpG: 63/Downstream/184489
Nearest cancer related gene
UHRF2(TSG, No orient, 0)
Upstream sequence
CAAATTAGGTTTTTCTGTACATTGCATAAAACTTTAGTTGTCTTTGGTAATCATAAGCCATATGGTTTTCTCTCTCCTCAGATACCCAGAAAGCGGTACT
Downstream sequence
CTAGAAATGAATGTCAAGGATCTTAGACCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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